Liver Diseases
Biochemical Mechanisms and New Therapeutic
Insights
Shakir Ali, Scott L. Friedman and Derek A. Mann (eds.)
ISBN 978-1-57808-399-2; 2006; 580 pages (2 vols.), hc; US $
196.00
Buy
Now
This book presents state-of-art information summarizing the current understanding
of a range of liver diseases, and reviews some key diagnostic and therapeutic
advances. The
book is a collection of selected clinical and scientific topics divided into
two volumes, each divided into two sections. The first volume treats the cellular,
biochemical and immunological mechanisms underlying liver diseases; the second
focuses on clinical liver disease pathophysiology and related diagnostics and
therapeutic insights.
It is hoped that the target readers - hepatologists, clinicians, researchers
and cademicians - will be exposed to new ideas, and subjects beyond their
own scientific disciplines. In addition, students and all those who wish to
enlarge their knowledge of advances in the field of liver diseases will find
this book a good source of information.
CONTENTS :
Volume 1: Liver Diseases: Pathways, Mediators and Regulation
•
Section I: Liver Diseases: Mediators and Regulation
. Ubiquitin - Proteasome Pathway in the Pathogenesis of Liver Disease:
Samuel W. French and
Fawzia
. Bardag-Gorce; Collagen Gene Regulation in the Hepatic Stellate Cell:
Branko Stefanovic and
Richard A.
. Rippe; CYP2F1-Biochemical and Toxicological Aspects and Role in Alcohol-induced
Liver Injury:
Arthur I.
. Cederbaum; Alcohol and Methyl Transfer: Implications for Alcohol-Related
Hepatocarcinogenesis:
Felix Stickel et al.; Menthionine Adenosyltransferase
and S-adenosylmethionine in Liver Health and Disease:
Shelly C. Lu and
José M. Mato; Acetone Metabolism in the Liver:
Med. Habil.
. Miklós Péter Kalapos;Oxidative Stress and Liver Fibrosis:
From Liver Injury to Modulation of Cell Signalling and Response:
Elena Zamara
et al.; Role of Nitric Oxide in Liver Disorders: Pablo Muriel; Renin-Angiotensin
System in Liver Fibrosis:
Hitoshi Yoshiji et al.
•
Section II: Immunological Basis of Liver Injury
. Cell and Molecular Mechanisms in the Development of Chronic Liver Inflammation:
Simon C. Afford and
Patricia F. Lalor; Role of Activated Macrophages
in Liver Disease:
Ion Deaciuc and
Craig J. McClain; Investigations
into Basis for Immune Recognition of Cellular Targets in Primary Biliary Cirrhosis:
Ruth Joplin; Cross Talk of Hepatocytes and Nonparenchymal Liver Cells
in Physiology and Pathology:
Monoxides and
Eicosanoids: Zbigniew Kmiec; Activity of Cytokines
in Chronic HCV Infection and
Influence of Antiviral Drugs:
Tadeusz Wojciech Lapinski; Role of Chemokines
in Liver Pathophysiology:
Fabio Marra
Volume 2: Clinical Liver Diseases: Pathophysiology, Diagnostic and Therapeutic
Insights
•
Section III: Clinical Liver Disease Pathophysiology
Nonalcoholic Fatty Liver Diseases: Clinical and Pathophysiological Features:
Frank A. Anania; Genetic
Basis of Hepatocellular Cancer:
Sigal Tal-Kremer et al.; Haemochromatosis:
Recent Advances:
AJM Davis and
WM Rosenberg; Pathophysiology of
Cirrhotic Ascites: Recent Advances:
George Therapondos and
Florence
Wong; Cryptogenic Hepatitis:
Isabelle Chemin; HIV-1 and the Liver:
Sandro Vento and
Francesca Cainelli; Cell Death by Necrosis: Mechanisms
and Interception in the Liver:
Shakir Ali; Fulminant Hepatic Failure:
Etiology, Pathogenesis, and Treatment:
Eran Elinav and
Rafael Bruckl
•
Section IV: Therapeutic and Diagnostic Insights
Advances in Biology and Therapy of Hepatitis B Virus Infection:
Frank Tacke
et al.; Hepatitis C Virus:
Molecular Virology and Therapeutic Targets:
Andrew Macdonald and
Mark
Harris; Drug Targeting to
Hepatic Stellate Cells: A New Strategy to Treat Liver Fibrosis:
Leonie Beljaars
et al.; Developing
Therapeutic Strategies for Hepatic Fibrosis:
Ichiro Shimizu; Liver Disease,
Oxidative Stress and
Ursodeoxycholic Acid:
Predrag Ljubuncic and
Arieh Bomzon; Plasma
TGF-b as a Diagnostic and
Prognostic Marker:
M. Antoine et al.; Hepatocytes as the Gold Standard
for Predicting in-vivo
Hepatotoxicity of Xenobiotics Using Accelerated Cytotoxicity Mechanism Screening
Techniques:
Peter J.O’Brien et al.
