Modern Industrial Microbiology
and Biotechnology
Nduka Okafor: Adjunct Professor, Department of Biological
Sciences, Clemson University, Clemson, South Carolina, USA
ISBN 978-1-57808-513-2; June 2007; 550 pages; pb; US $ 66.60
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This book is directed towards undergraduates and beginning graduate students
in microbiology, food science and chemical engineering. Those studying pharmacy,
biochemistry and general biology will find it of interest. The section on waste
disposal will be of interest to civil engineering and public health students
and practitioners. For the benefit of those students who may be unfamiliar with
the basic biological assumptions underlying industrial microbiology, such as
students of chemical and civil engineering, elements of biology and microbiology
are introduced.
The new elements which have necessitated the shift in paradigm in industrial
microbiology such as bioinformatics, genomics, proteomics, site-directed mutation,
metabolic engineering, the human genome project and others are also introduced
and their relevance to industrial microbiology and biotechnology indicated.
As many references as space will permit are included.
The various applications of industrial microbiology are covered broadly, and
the chapters are grouped to reflect these applications. The emphasis throughout,
however, is on the physiological, biochemical principles, and where possible,
the genomic principles behind these applications.
Contents:
Introduction
. Introduction: Scope of Biotechnology and Industrial Microbiology
Biological Basis of Productivity in Industrial Microbiology
. Some Microorganism Commonly Used in Industrial Microbiology and Biotechnology;
Aspects of Molecular Biology and Bioinformatics of Relevance in Industrial Microbiology
and Biotechnology; Industrial Media and the Nutrition of Industrial Organisms;
Metabolic Pathways for the Biosynthesis of Industrial Microbiology Products;
Over-Production of Metabolites of Industrial Micro-Organisms; Screening for
Productive Strains and Strain Improvement in Biotechnological Organisms; The
Preservation of the Gene Pool in Industrial Organisms: Culture Collections Basic
Operations in Industrial Fermentations
. Fermentors and Fermentor Operation; Extraction of Fermentation Products;
Sterility in Industrial
Microbiology
Alcohol-based Fermentation Industries
. Production of Beer; Production of Wines and Spirits; Production of
Vinegar
Use of Whole Cells for Food Related Purposes
. Single Cell Protein (SCP); Yeast Production; Production of Microbial
Insecticides; The Manufacture of Rhizobium Inoculants; Production of Fermented
Foods
Production of Metabolites as Bulk Chemicals or as Inputs in Other Processes
. Production of Organic Acids and Industrial Alcohol; Production of Amino
Acids by Fermentation; Biocatalysts: Immobilized Enzymes and Immobilized Cells;
Mining Microbiology: Ore Leaching (Bioleaching) by Micro-organisms
Production of Commodities of Medical Importance
. Production of Antibiotics and Anti-Tumor Agents; Production of Ergot
Alkaloids; Microbial Transformation and Steroids and Sterols;Vaccines; Drug
Discovery in Microbial Metabolites: The Search for Microbial Products with Bioactive
Properties
Waste Disposal
. Treatment of Wastes in Industry
Glossary